منابع مشابه
Hexokinase type I multiplicity in human erythrocytes.
Hexokinase I in human erythrocytes exists in multiple molecular forms that differ in isoelectric points. By means of Western blotting and immunodetection of total glucose-phosphorylating activity by using an antibody raised in rabbit against homogeneous human placenta hexokinase I, a single protein band was detected. Identical results were also obtained by immunoaffinity chromatography of the p...
متن کاملIsozymes of mammalian hexokinase: structure, subcellular localization and metabolic function.
The first step in metabolism of glucose (Glc) is usually phosphorylation, catalyzed by hexokinase. However, the Glc-6-P produced can then enter one or more of several alternative pathways. Selective expression of isozymic forms of hexokinase, differing in catalytic and regulatory properties as well as subcellular localization, is likely to be an important factor in determining the pattern of Gl...
متن کاملHuman carbonic anhydrases. VI. Levels of isozymes in old and young erythrocytes and in various tissues.
The more acidic, minor isozymes of human carbonic anhydrase types B and C are present in higher concentrations in the older erythrocyte populations. The levels of all of these isozymes can be determined quantitatively by immunochemical methods following their separation by electiofocusing. A wide variety of human tissues have been assayed for carbonic anhydrases. Significant levels of the C typ...
متن کاملIdentification of thymidine nucleotidase and deoxyribonucleotidase activities among normal isozymes of 5'-nucleotidase in human erythrocytes.
The persistence of normal thymidine nucleotidase (ThyNase) activity in subjects with pyrimidine nucleotidase (PyrNase) deficiency suggested the possible existence of separate isozymes in normal human erythrocytes. This hypothesis was confirmed by studies of PyrNase-deficient individuals from five unrelated families. Erythrocytes deficient in PyrNase retained normal activity of an enzyme system ...
متن کاملalteration in membrane protein, antioxidant status and hexokinase activity in erythrocytes of ccl4- induced cirrhotic rats.
several studies have shown that hepatocyte membrane composition changes in patients with cholestasis and cirrhosis. these alterations that are because of intracellular oxidative stress are supposed to be reflected in erythrocyte membrane. the aim of this study was to investigate the modification of erythrocyte membrane along with hexokinase and antioxidant enzymes during development of cirrhosi...
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ژورنال
عنوان ژورنال: Science
سال: 1968
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.159.3815.650